Ilgiz Mufazalov, PhD

Postdoctoral Researcher
Diabetes Center
Publications: 

Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.

Immunity

Dmitrieva-Posocco O, Dzutsev A, Posocco DF, Hou V, Yuan W, Thovarai V, Mufazalov IA, Gunzer M, Shilovskiy IP, Khaitov MR, Trinchieri G, Waisman A, Grivennikov SI

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity.

Proceedings of the National Academy of Sciences of the United States of America

Atretkhany KN, Mufazalov IA, Dunst J, Kuchmiy A, Gogoleva VS, Andruszewski D, Drutskaya MS, Faustman DL, Schwabenland M, Prinz M, Kruglov AA, Waisman A, Nedospasov SA

Cytokines as Mediators of Neuroinflammation in Experimental Autoimmune Encephalomyelitis.

Biochemistry. Biokhimiia

Gogoleva VS, Atretkhany KN, Drutskaya MS, Mufazalov IA, Kruglov AA, Nedospasov SA

Regulation of IL-1 signaling by the decoy receptor IL-1R2.

Journal of molecular medicine (Berlin, Germany)

Schlüter T, Schelmbauer C, Karram K, Mufazalov IA

Expression of IL-17F is associated with non-pathogenic Th17 cells.

Journal of molecular medicine (Berlin, Germany)

Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC, Waisman A

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.

Science immunology

Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL

A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.

Journal of autoimmunity

Göschl L, Preglej T, Hamminger P, Bonelli M, Andersen L, Boucheron N, Gülich AF, Müller L, Saferding V, Mufazalov IA, Hirahara K, Seiser C, Matthias P, Penz T, Schuster M, Bock C, Waisman A, Steiner G, Ellmeier W

Balanced Bcl-3 expression in murine CD4+ T cells is required for generation of encephalitogenic Th17 cells.

European journal of immunology

Mufazalov IA, Kuschmann J, Andruszewski D, Masri J, Gabriel LA, Adams P, Reissig S, Hövelmeyer N, Waisman A

Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.

Nature communications

Reißig S, Tang Y, Nikolaev A, Gerlach K, Wolf C, Davari K, Gallus C, Masri J, Mufazalov IA, Neurath MF, Wunderlich FT, Schattenberg JM, Galle PR, Weigmann B, Waisman A, Glasmacher E, Hövelmeyer N

TGF-ß inhibitor Smad7 regulates dendritic cell-induced autoimmunity.

Proceedings of the National Academy of Sciences of the United States of America

Lukas D, Yogev N, Kel JM, Regen T, Mufazalov IA, Tang Y, Wanke F, Reizis B, Müller W, Kurschus FC, Prinz M, Kleiter I, Clausen BE, Waisman A

EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.

Cell reports

Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, Reißig S, Lacher SM, Reichhold C, Mufazalov IA, Ben-Nun A, Kuhlmann T, Wettschureck N, Sailer AW, Rajewsky K, Casola S, Waisman A, Kurschus FC

IL-1 signaling is critical for expansion but not generation of autoreactive GM-CSF+ Th17 cells.

The EMBO journal

Mufazalov IA, Schelmbauer C, Regen T, Kuschmann J, Wanke F, Gabriel LA, Hauptmann J, Müller W, Pinteaux E, Kurschus FC, Waisman A

Characterization of a conditional interleukin-1 receptor 1 mouse mutant using the Cre/LoxP system.

European journal of immunology

Abdulaal WH, Walker CR, Costello R, Redondo-Castro E, Mufazalov IA, Papaemmanouil A, Rothwell NJ, Allan SM, Waisman A, Pinteaux E, Müller W

Isolation of Central Nervous System (CNS) Infiltrating Cells.

Methods in molecular biology (Clifton, N.J.)

Mufazalov IA, Waisman A

Mouse lymphomyeloid cells can function with significantly decreased expression levels of cytochrome C.

Biochemistry. Biokhimiia

Shilov ES, Kislyakov IV, Gorshkova EA, Zvartsev RV, Drutskaya MS, Mufazalov IA, Skulachev VP, Nedospasov SA

Cytochrome c: the Achilles' heel in apoptosis.

Cellular and molecular life sciences : CMLS

Kulikov AV, Shilov ES, Mufazalov IA, Gogvadze V, Nedospasov SA, Zhivotovsky B

[Preparation and characterization of mouse embryonic fibroblasts with K72W mutation in somatic cytochrome C gene].

Molekuliarnaia biologiia

Mufazalov IA, Pen'kov DN, Cherniak BV, Pletiushkina OIu, Vysokikh MIu, Kirpichnikov MP, Dolgikh DA, Kruglov AA, Kuprash DV, Skulachev VP, Nedospasov SA

[Chromosomal localization and molecular organization of human genomic fragment containing TNF/LT locus in transgenic mice].

Molekuliarnaia biologiia

Galimov AR, Kruglov AA, Bol'sheva NL, Iurkevich OIu, Lipin'sh DIa, Mufazalov IA, Kuprash DV, Nedospasov SA

[Protein kinases abundantly expressed in undifferentiated human ESC lines and derived embryoid bodies].

Tsitologiia

Filonenko ES, Volchkov PIu, Mufazalov IA, Kiselev SL, Lagar'kova MA